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METHOD OF TISSUE TRANSFER AND RETRIEVALPatent No. 5,858,781Issued: January 12, 1999 Patent No. 5,866,417Issued: February 2, 1999 Inventors: John R. Matyas, 1606 21 Avenue NW, Calgary, Alberta T2M 1M1, Canada; Jerome B. Rattner, 35 Pt. McKay Court, Calgary, Alberta T3B 5B7, Canada |
The Tissue Transfer method of the '417 patent consists of transferring intact, organized cells from the surfaces of biological tissues or organs to a transfer substrate. A surface of the tissue or organ is selected, in most cases, a freshly cut surface. At least one layer of intact cells is transferred by adhesion of the cells to a transfer substrate, which is a membrane, film, plate or liquid layer bound to a solid structure. The substrate is brought into contact with the selected surface and removed. A layer of cells is removed by the adhesion of the cells to the substrate and the cells retain the organization of the organ or tissue.
The '781 patent covers a method and apparatus for retrieving glomeruli dislodged from renal biopsy cores during the biopsy procedure and immobilizing the glomeruli on a membrane substrate. The morphological quality of these glomeruli is such that they can be used for diagnostic evaluation.
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