Patent number: 8961951

Baculoviruses with enhanced virion production and a method for the production of baculoviruses

Original Assignee: Boyce Thompson Institute for Plant Research, Inc.

Field of technology: Biotech

Patent granted on: Tue, 24 Feb 2015

Patent drawing

Abstract

The present invention provides a method for restoring budding capability to GP64null baculoviruses including gp64null AcMNPV by expressing therein a portion of the VSV G protein gene or a truncated “stem” portion of the GP64 gene. Other embodiments provide methods to use portions of the G-stem or GP64 protein to target foreign proteins for display on virions.